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12 Cards in this Set
- Front
- Back
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Differentials for microscopic hematuria |
BPH Interstitial nephritis Papillary necrosis Renal stones Cystic kidney disease Renal vascular injury |
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Gross hematuria |
Sickle Cell Disease IgA Nephropathy
Excluding anatomic cause - maglignancy |
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Renal Biopsy |
1. Hematoxylin and Eosin H and E - assess cellularity and architecture 2. Periodic acid Schiff - stain CHO moiety in membranes of the glomerular tuft and tubules 3. Jones Methenamine Silver - enhances BM structure 4. Congo red - amyloid deposits 5. Masson’s trichome - identify collagen deposition; assess degree of glomerulosclerosis and interstitial fibrosis |
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Major causes of Papillary Necrosis |
Analgesic Nephropathy Diabetes with UTI Sickle Cell Nephropathy Prolonged NSAID use (rare) |
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Triad of chronic lead intoxication |
Saturnine gout Hypertension Impaired kidney function |
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Kidney Biopsy Indications |
glomerulonephritis, vasculitis, interstitial nephritis, myeloma kidney, HUS and TTP, and allograft dysfunction |
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Transient Proteinuria |
Fever Exercise Obesity Sleep apnea Emotional stress Congestive Heart Failure |
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Renal diseases with ERYTHROCYTOSIS |
urinary tract obstruction polycystic kidney disease renal vascular disease renal cell carcinoma |
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Hypokalemia Metabolic Acidosis |
adrenal adenoma unilateral renal artery stenosis ACTH-secreting tumors licorice abuse potassium-sparing diuretics. |
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Normal Benign Proteinuria |
8-10mg urine Albumin in 24h <150mg urine protein in 24h <30mg/g UACR Negative dipstick proteinuria |
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Common causes of ISOLATED HEMATURIA |
stones neoplasm Tuberculosis trauma prostatitis |
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Common causes of ISOLATED Glomerular Hematuria - Dysmorphic hematuria |
IgA nephropathy hereditary nephritis thin basement membrane disease |
